"Review by Grégoire LE GAL The 8th edition of a "bedtime reading“ work for physicians involved in the management of Venous Thromboembolic Disease (VTED) (“Antithrombotic and Thrombolytic Therapy, American College of Chest Physicians Evidence- Based Practice Guidelines”, 8th edition) has just been published. This new volume, which is almost 1000 pages long, presents a state of the art description of antithrombotic agents (platelet anti-aggregants, anticoagulants, thrombolytics), their indications (VTED, atrial fibrillation, valvular heart disease, coronary artery disease, peripheral ar"

Full text

"rogress – 45 rue des Saints Pères, Paris, France SUMMARY The aim of this paper is to demonstrate the major role played by the new computerized imaging tools available today in the fields of morphology and vascular anatomy. For anatomical studies or educational purposes, they enhance classic techniques. Three-dimensional reconstruction, which is already used in daily clinical practice, will be the basis for computation of validated volumetric protocols enhancing our diagnostic, prognostic, and therapeutic methods. It is also a fantastic educational tool: interactivity and virtual di"

Full text

" in the methodology. A proper prevalence assessment is not easily done and requires time and effort. Most studies have just focused on prevalence of leg ulcers of all causes and only a few have really validated the leg ulcer diagnosis objectively by use of hand-held Doppler, color Doppler ultrasound, or plethysmography. There are many pitfalls in performing a prevalence study of venous leg ulcers which introduce a risk of misinterpretation of the true prevalence. Some of these pitfalls and their likely effects are presented. Based on the available and most qualitative studies the overall preva"

Full text

"on of venoactive drugs (VADs) in 10 countries (mostly European) in a recent survey: 17 million people per year are treated with VADs,* while 140 million among the adult population in these countries complain of leg symptoms.** The relationship between venous symptoms and venous signs is tenuous, as it is between venous symptoms and venous reflux. Therefore the medical literature concludes that these venous symptoms are nonspecific. This raises the question of the value of the available diagnostic tools and their specificity for venous symptoms. The present review considers tools currently used"

Full text

"o conservative therapies, and the presence of non-healing or recurrent ulcers may lead one to consider surgery. However, even if surgery is properly indicated, traditional techniques such as femoral transposition and valve transplantation are not always suitable, and in these cases a de novo valve reconstruction represents a surgical opportunity. Our neovalve reconstruction technique consists in creating an intimal flap by performing a wall dissection. The purpose is to create an antireflux mechanism that reduces venous hypertension. This technique was applied from December 2000 in 39 selected"

Full text

"se research, the aim of which is to establish a cause that will allow us to prevent or at least slow down this undesirable process. We have investigated the role played by inflammatory cells, especially leukocytes, in the etiology of varicose veins. We hypothesize that venous insufficiency could result from the interaction between two processes: tissue aging and abnormalities in the leukocyte/endothelial cell interaction. These two processes, the individual contribution of which depends on the context, are believed to compound each other resulting in venous insufficiency. Thus, in young indivi"

Full text

"ricose veins in chronic venous disease patients. Specimens were obtained from aortocoronary bypass and varicose vein surgery and were differentiated according to age: patients under and over 50. This approach showed that inflammatory cells play an important role in both the aging process and the development of varicose veins. Oscar Maleti and Marzia Lugli from Modena, Italy, give an overview of their experiences with the revolutionary surgical technique they have developed in which a neovalve is created in patients with postthrombotic syndrome and massive, deep axial reflux. The essential "

Full text

"struction in postthrombotic syndrome. Technique, indications, and results O. Maleti, M. Lugli - Phlebolymphology - 2008; 15 (4): 131-136 Assessment of treatment efficacy on venous symptoms: the example of Daflon 500 mg F. Pitsch - Phlebolymphology - 2008; 15 (4): 137-142 Prevalence of venous leg ulcer: the importance of the data collection method O. Nelzen - Phlebolymphology - 2008; 15 (4): 143-150 New computer tools for virtual dissection to study the anatomy of the vascular system J.-F. Uhl, S. Ordureau - Phlebolymphology - 2008; 15 (4): 151-155 ABOUT NEW ARTICLES A Review b"

Full text