Chronic pelvic pain associated with pelvic congestion syndrome and the benefit of Daflon 500 mg: a review*

Feza BURAK1 Tonguc GUNDUZ2 Mehmet SIMSEK2 Omur TASKIN1,2 Departments of Obstetrics and Gynecology Ìnonu University 1, Malatya and Akdeniz University 2, Antalya School of Medicine * This review is based on the following publication: 1) Taskin O, Uryan I I, Buhur A, et al. The Effects of Daflon on Pelvic Pain in Women with Taylor Syndrome. J Am Assoc Gynecol Laparosc. 1996;3(4, Supplement):S49, and 2) Simsek M, Burak F, Taskin O. Effects of micronized purified flavonoid fraction (Daflon) on pelvic pain in women with laparoscopically diagnosed pelvic congestion syndrome: a randomized crossover trial. Clin Exp Obstet Gynecol. 2007;34(2):96-98. SUMMARY Chronic…

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Pharmacological treatment of chronic venous disorders

Michel PERRIN1 and George GEROULAKOS2 1. Vascular Surgeon, Chassieu, France 2. Consultant Vascular Surgeon, Ealing and Charing Cross Hospital, Senior Lecturer, Department of Vascular Surgery, Imperial College of Science Technology and Medicine, London, UK The term chronic venous disorder (CVD) is used to denote all abnormal clinical changes that result from venous disease of the lower extremities, and that have a chronic course.1 According to this definition, CVD includes patients who present with so-called symptoms and/or signs of venous disease that characterize each class of CVD in the Clinical, Etiological, Anatomical, Pathophysiological (CEAP) classification,2 from class C0s to class C6….

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Stripping of the great saphenous vein under micronized purified flavonoid fraction (MPFF) protection (results of the Russian multicenter controlled trial DEFANCE)

Victor S. SAVELJEV2 Anatoly V. POKROVSKY1 Alexander I. KIRIENKO2 Vadim YU. BOGACHEV2 Igor A. ZOLOTUKHIN2 Sergey V. SAPELKIN1 SUMMARY This paper presents the results of the DEFANCE study (Daflon 500 mg* – assEssment of eFficacy ANd safety for Combined phlEbectomy study). The aim of the study was to compare the intensity of postoperative pain, the size of postoperative hematoma, and quality-of-life score between two groups of patients: • a Daflon 500 mg group: patients who underwent stripping of the great saphenous vein (GSV) and were treated with Daflon 500 mg 14 days before and 30 days after surgery • a…

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