Residual rates of reflux and obstruction and their correlation to post-thrombotic syndrome in a randomized study on catheter-directed thrombolysis for deep vein thrombosis.

Haig Y, Enden T, Slagsvold CE, Sandvik L, Sandset PM, Kløw NE. J Vasc Surg: Venous Lymphat Disord. 2014;2:123-130. Catheter-directed thrombolysis, venous abnormalities, and postthrombotic syndrome Despite appropriate anticoagulant therapy, at least 1 of every 2 to 3 patients with proximal deep vein thrombosis (DVT) of the lower extremities will develop (severe) postthrombotic sequelae (PTS). Among parameters that have been found to be associated with an increased risk of PTS are venous thrombosis of the common femoral or iliac vein, obesity, previous ipsilateral DVT, older age, and female sex.1,2 By contrast, the role played by the development of venous reflux…

Full text