Presence of varices after operative treatment: a review

Part 1: This is the first of 2 chapters that will comprise the ‘PREsence of Varices After operatIve Treatment (PREVAIT)’. These 2 chapters will  be published in the journal consecutively. Michel Perrin, MD Vascular Surgery, 26 Chemin de Decines, F-69680 Chassieu, France Abstract Background: PREsence of Varices after operatIve Treatment (PREVAIT ) occurs in 13% to 65% of patients and remains a debilitating and  costly problem. The first part of this review provides an overview of the current understanding of the etiology and pathogenesis of PREVAIT . Methods: A PubMed search was conducted in English and French for the years…

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Thrombosis and pulmonary embolism risk in patients undergoing varicose vein surgery

Andreas Oesch Chirurgie FMH, Kramgasse 16, CH 3011, Bern, Switzerland ABSTRACT Varicose veins are not by themselves dangerous. Nevertheless, when treating them, it is important to prevent the occurrence of complications with potentially serious consequences such as deep vein thrombosis or pulmonary embolism. Vein operations are among the procedures carrying the lowest risk of all surgical interventions. Publications on thromboembolism after vein surgery show a striking discrepancy in the number of reported cases of thromboembolism, which is partially due to the different methods used to record them. Most thromboses are localized in the calf and their damage potential is limited,…

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Review and Comment of the 2011 Clinical Practice Guidelines of the Society for Vascular Surgery and the American Venous Forum

Gloviczki P, Comerota AJ, Dalsing MC, et al. The care of patients with varicose veins and associated chronic venous diseases: Clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum. J Vasc Surg. 2011;53:2S-48S. Marzia LUGLI Modena, Italy Oscar MALETI Modena, Italy Michel PERRIN Lyon, France ABSTRACT The Clinical Practice Guidelines of The Society for Vascular Surgery and The American Venous Forum, published in the 2011 Journal of Vascular Surgery supplement, is the most complete document on the management of varicose veins ever published in English. It is the work of leading members of the American…

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Stripping of the great saphenous vein under micronized purified flavonoid fraction (MPFF) protection (results of the Russian multicenter controlled trial DEFANCE)

Victor S. SAVELJEV2 Anatoly V. POKROVSKY1 Alexander I. KIRIENKO2 Vadim YU. BOGACHEV2 Igor A. ZOLOTUKHIN2 Sergey V. SAPELKIN1 SUMMARY This paper presents the results of the DEFANCE study (Daflon 500 mg* – assEssment of eFficacy ANd safety for Combined phlEbectomy study). The aim of the study was to compare the intensity of postoperative pain, the size of postoperative hematoma, and quality-of-life score between two groups of patients: • a MPFF at a dose of 500 mg group: patients who underwent stripping of the great saphenous vein (GSV) and were treated with MPFF at a dose of 500 mg 14 days…

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