Phlebolymphology N°58

Phlebolymphology N°58 – Editorial

Dear Readers This new issue of Phlebolymphology includes contributions from world leaders in the field, and demonstrates once more the fascinating variety of our discipline. In this issue you will find: Paolo PRANDONI from the University of Padua is one of the world’s top authorities in clinical research on venous thromboembolism, and he has published several landmark articles in this field. In his current article he discusses the ways in which recurrences of venous thromboembolism can be prevented. This is a problem of very high practical interest for doctors, as recurrent episodes of venous thrombosis are among the deciding risk…

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Phlebolymphology N°58 (Vol 15 – N°1 – 2008)

EDITORIAL Editorial H. Partsch – Phlebolymphology – 2008 ; 15(1): 2 PHLEBOLOGY Recurrence of venous thromboembolism and its prevention P. Prandoni – Phlebolymphology – 2008; 15 (1): 3 Iliac vein outflow obstruction in ‘primary’ chronic venous disease S. Raju – Phlebolymphology – 2008; 15 (1): 12 Pelviperineal venous insufficiency and varicose veins of the lower limbs V. Stvrtinova – Phlebolymphology – 2008; 15 (1): 17 Skin necrosis as a complication of compression in the treatment of venous disease and in prevention of venous thromboembolism S. Raju – Phlebolymphology – 2008; 15 (1): 27 LYMPHOLOGY Towards a better understanding of lymph…

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Recurrence of venous thromboembolism and its prevention

Paolo PRANDONI Department of Medical and Surgical Sciences Department of Medical and Surgical Sciences Thromboembolism Unit University of Padua, Italy ABSTRACT The risk of recurrent venous thromboembolism (VTE) approaches 40% in all patients after 10 years of follow-up. This risk is higher in patients with permanent risk factors for thrombosis, such as active cancer, prolonged immobilization because of disease, and antiphospholipid antibody syndrome; in patients with idiopathic presentation; and in carriers of several thrombophilic abnormalities, including carriers of AT, protein C or S, increased factor VIII, hyperhomocysteinemia, homozygous carriers of factor V Leiden or prothrombin G20210A variant, and carriers of…

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Iliac vein outflow obstruction in ‘primary’ chronic venous disease

Seshadri RAJU Emeritus Professor of Surgery and Honorary Surgeon, University of Mississippi Medical Center and River Oaks Hospital, Flowood, MS, USA ABSTRACT The nonthrombotic iliac vein lesion (NIVL) was first described in 1908. Since then, it has become clear that the lesion is present in over half the general population in silent form. A clinical syndrome variously known as May- Thurner syndrome, Cockett syndrome, or “iliac vein compression syndrome”, caused by NIVL, is thought to be a rare form of chronic venous disease (CVD). However, with liberal use of intravascular ultrasound (IVUS), the lesion is found in over 90% of…

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Pelviperineal venous insufficiency and varicose veins of the lower limbs

Edgar BALIAN, Jean-Louis LASRY, Gérard COPPÉ, Hervé BORIE, Agnès LEROUX, Dominique BRYON, Stéphane KOVARSKY Private Hospital, Antony, France. Dept. of Cardiology and Interventional Radiology Investigation and treatment of pelvic venous insufficiency (PVI) in women to date has primarily involved its most familiar clinical presentation, ie, pelvic congestion syndrome (PCS) accurately described by Hobbs.1 For the last few years,2 more attention has focused on involvement of PVI in the pathogenesis of primary varicose veins or recurring varicosities of the lower limbs. This finding has been confirmed by a national epidemiologic survey that evaluated the potential incidence of pelvic pain of venous…

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Skin necrosis as a complication of compression in the treatment of venous disease and in prevention of venous thromboembolism

Michel PERRIN Vascular Surgeon, Chassieu, France BACKGROUND The main concern with compression treatment for chronic venous disease of the lower limb remains compliance, which is difficult to assess depending on the clinical status. Complications like skin allergic reaction and eczema,1 and nerve palsy,2 have been reported, but the most severe is skin necrosis in diabetics or patients with peripheral arterial disease of the lower limbs. There is a consensus for contraindicating compression in patients whose ankle/brachial index (ABI) is less than 0.6, but the arterial disease is not always identified. Diabetes also carries a potential risk of skin wound, but…

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Towards a better understanding of lymph circulation

Olivier STÜCKER*, Catherine PONS-HIMBERT*, and Elisabeth LAEMMEL** *CEROM **Université Paris 7 Paris, France SUMMARY The lymphatic system was for years considered an “accessory” system and was neglected in comparison with the vascular system, which appeared much more crucial. In the last decade, researchers have become interested in lymphatic function since many diseases seem to interact with it (cancer, inflammation, infection, auto-immunity). The lymphatic system is harder to study than its vascular counterpart as its vessels are ill-defined, almost invisible. Intravital microscopy alone correctly visualizes these structures, thus shedding light on their function and quantifying their movements. This paper focuses on…

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The Second American Venous Forum, Servier Traveling Fellowship A report from Reagan W. Quan (Washington, DC, USA), recipient of the 2007 AVF/Servier Fellowship

A report from Reagan W. Quan (Washington, DC, USA), recipient of the 2007 AVF/Servier Fellowship Reagan W. QUAN Vascular and Endovascular Surgery, Walter Reed Army Medical Center, DC 20307 Washington, USA The Servier Traveling Fellowship was established for postgraduate vascular physicians or surgeons. It is designed to help further understanding between European and American physicians in the treatment of venous diseases. Following the completion of my Vascular Surgery Fellowship at Walter Reed Army Medical Center in Washington, DC, I was afforded a once-in-a-lifetime opportunity. As a result of my research on Repair of Military Venous Trauma and Thromboembolic Events, much…

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