Effectiveness of micronized purified flavonoid fraction–based conservative treatment in chronic venous edema

Vadim Yu BOGACHEV, MD, PhD On behalf of the VAP-PRO-C3 study investigators group. Department of Faculty Surgery No. 2, Pirogov Russian National Research Medical University (RNRMU), Moscow, Russia Abstract Aim: This study assessed the effectiveness of micronized purified flavonoid fraction (MPFF)-based conservative treatment in patients with chronic venous edema (CVE) as part of an observational program that evaluated the management of patients with CVE caused by the primary forms of chronic venous disease (CVD) in real clinical practice. Materials and methods. The VAP-C3 (Vein Act Prolonged-C3; NCT03722836) prospective, single-arm, observational study was conducted in Russia in adult outpatients with CVD…

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Deep vein thrombosis and air travel: risk management in 2015

Deep vein thrombosis and air travel: risk management in 2015 Michèle CAZAUBON Vascular Unit, Vein Clinic, American Hospital of Paris, France. Abstract Long-haul flights increase the risk of venous thromboembolism (VTE) for several weeks after the flight by 3-fold among passengers compared with the general population. The risk increases with flight duration and persists for several weeks (until week 8) after landing. This risk is not the same for all passengers and should be determined before any long flight, especially among frequent travellers. The calculation of risk is based on simple clinical data, easily obtained by the treating physician. If…

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Postinterventional compression in phlebology: evidence and empirical observations

Postinterventional compression in phlebology: evidence and empirical observations Giovanni MOSTI Angiology Department, MD Barbantini Clinic, Italy Abstract There is almost a general agreement on the effectiveness of compression therapy in preventing unwanted side effects after procedures to remove superficial venous reflux. However, there is still a great debate on which material and compression pressure to use. In order to exert its effects, compression must occlude the vein segments ruptured by surgical or endovenous procedures. At the thigh, the critical segment in every venous intervention, the intravenous pressure is about 40 mm Hg and a higher compression pressure is necessary in…

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